STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (362 aa)    
Predicted Functional Partners:
mvaD
Diphosphomevalonate decarboxylase.
 
  
 0.994
AFN47093.1
Phosphomevalonate kinase.
  
 0.993
mvk
Mevalonate kinase.
 
  
 0.956
AFN47543.1
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 
 0.915
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.911
uppS_2
Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
    
 0.908
AFN45052.1
Transporter, lactate permease family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
  
  
 0.685
nifJ
Pyruvate synthase.
  
  
 0.678
guaA
GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.
  
  
 0.621
AFN45311.1
Putative hydroxymethylglutaryl-CoA synthase.
 
  
 0.609
Your Current Organism:
Pseudopropionibacterium propionicum
NCBI taxonomy Id: 767029
Other names: P. propionicum F0230a, Propionibacterium propionicum F0230a, Pseudopropionibacterium propionicum F0230a
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