STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvaDDiphosphomevalonate decarboxylase. (327 aa)    
Predicted Functional Partners:
AFN47093.1
Phosphomevalonate kinase.
 
 0.999
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.995
mvk
Mevalonate kinase.
 
  
 0.990
AFN47543.1
Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
 0.937
AFN45311.1
Putative hydroxymethylglutaryl-CoA synthase.
 
 
 0.928
uppS_2
Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
   
 0.916
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
     
  0.900
lysS
lysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
      0.576
AFN45932.1
Tripartite tricarboxylate transporter TctA family protein.
 
     0.482
AFN46410.1
Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
       0.437
Your Current Organism:
Pseudopropionibacterium propionicum
NCBI taxonomy Id: 767029
Other names: P. propionicum F0230a, Propionibacterium propionicum F0230a, Pseudopropionibacterium propionicum F0230a
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