| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFN45079.1 | AFN46061.1 | HMPREF9154_1509 | HMPREF9154_1605 | Phosphoribosyl transferase domain protein. | Prephenate dehydrogenase. | 0.829 |
| AFN45079.1 | apt | HMPREF9154_1509 | HMPREF9154_1647 | Phosphoribosyl transferase domain protein. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.787 |
| AFN45079.1 | xerC | HMPREF9154_1509 | HMPREF9154_1107 | Phosphoribosyl transferase domain protein. | Site-specific recombinase, phage integrase family; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.844 |
| AFN46061.1 | AFN45079.1 | HMPREF9154_1605 | HMPREF9154_1509 | Prephenate dehydrogenase. | Phosphoribosyl transferase domain protein. | 0.829 |
| AFN46061.1 | apt | HMPREF9154_1605 | HMPREF9154_1647 | Prephenate dehydrogenase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.777 |
| AFN46061.1 | murG | HMPREF9154_1605 | HMPREF9154_1920 | Prephenate dehydrogenase. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.489 |
| AFN46061.1 | xerC | HMPREF9154_1605 | HMPREF9154_1107 | Prephenate dehydrogenase. | Site-specific recombinase, phage integrase family; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.737 |
| AFN46328.1 | xerC | HMPREF9154_1633 | HMPREF9154_1107 | RNAse H domain protein, YqgF family; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. | Site-specific recombinase, phage integrase family; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.589 |
| apt | AFN45079.1 | HMPREF9154_1647 | HMPREF9154_1509 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Phosphoribosyl transferase domain protein. | 0.787 |
| apt | AFN46061.1 | HMPREF9154_1647 | HMPREF9154_1605 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Prephenate dehydrogenase. | 0.777 |
| apt | xerC | HMPREF9154_1647 | HMPREF9154_1107 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Site-specific recombinase, phage integrase family; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.829 |
| def | rplS | HMPREF9154_1106 | HMPREF9154_1324 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.810 |
| def | xerC | HMPREF9154_1106 | HMPREF9154_1107 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Site-specific recombinase, phage integrase family; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.620 |
| ftsW | murG | HMPREF9154_1921 | HMPREF9154_1920 | Cell division protein FtsW; Belongs to the SEDS family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.998 |
| ftsW | spoIIIE | HMPREF9154_1921 | HMPREF9154_1366 | Cell division protein FtsW; Belongs to the SEDS family. | Stage III sporulation protein E. | 0.727 |
| ftsW | whiA | HMPREF9154_1921 | HMPREF9154_1066 | Cell division protein FtsW; Belongs to the SEDS family. | Sporulation regulator WhiA N-terminal domain protein; Involved in cell division and chromosome segregation. | 0.513 |
| ftsW | xerC | HMPREF9154_1921 | HMPREF9154_1107 | Cell division protein FtsW; Belongs to the SEDS family. | Site-specific recombinase, phage integrase family; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. | 0.547 |
| murG | AFN46061.1 | HMPREF9154_1920 | HMPREF9154_1605 | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | Prephenate dehydrogenase. | 0.489 |
| murG | ftsW | HMPREF9154_1920 | HMPREF9154_1921 | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | Cell division protein FtsW; Belongs to the SEDS family. | 0.998 |
| murG | spoIIIE | HMPREF9154_1920 | HMPREF9154_1366 | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | Stage III sporulation protein E. | 0.438 |