node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFN45111.1 | gmk | HMPREF9154_1988 | HMPREF9154_1620 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.911 |
AFN45111.1 | guaA | HMPREF9154_1988 | HMPREF9154_2130 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | 0.648 |
AFN45111.1 | pyk | HMPREF9154_1988 | HMPREF9154_1910 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.908 |
AFN45111.1 | relA | HMPREF9154_1988 | HMPREF9154_1645 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.901 |
AFN45147.1 | AFN45375.1 | HMPREF9154_0296 | HMPREF9154_1755 | 5'-nucleotidase. | 5'-nucleotidase, C-terminal domain protein; Belongs to the 5'-nucleotidase family. | 0.900 |
AFN45147.1 | apt | HMPREF9154_0296 | HMPREF9154_1647 | 5'-nucleotidase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.900 |
AFN45147.1 | gmk | HMPREF9154_0296 | HMPREF9154_1620 | 5'-nucleotidase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.900 |
AFN45147.1 | guaA | HMPREF9154_0296 | HMPREF9154_2130 | 5'-nucleotidase. | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | 0.900 |
AFN45147.1 | hpt | HMPREF9154_0296 | HMPREF9154_0416 | 5'-nucleotidase. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.900 |
AFN45147.1 | pyrF | HMPREF9154_0296 | HMPREF9154_1622 | 5'-nucleotidase. | Orotidine 5'-phosphate decarboxylase. | 0.900 |
AFN45375.1 | AFN45147.1 | HMPREF9154_1755 | HMPREF9154_0296 | 5'-nucleotidase, C-terminal domain protein; Belongs to the 5'-nucleotidase family. | 5'-nucleotidase. | 0.900 |
AFN45375.1 | apt | HMPREF9154_1755 | HMPREF9154_1647 | 5'-nucleotidase, C-terminal domain protein; Belongs to the 5'-nucleotidase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.936 |
AFN45375.1 | gmk | HMPREF9154_1755 | HMPREF9154_1620 | 5'-nucleotidase, C-terminal domain protein; Belongs to the 5'-nucleotidase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.902 |
AFN45375.1 | guaA | HMPREF9154_1755 | HMPREF9154_2130 | 5'-nucleotidase, C-terminal domain protein; Belongs to the 5'-nucleotidase family. | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | 0.914 |
AFN45375.1 | hpt | HMPREF9154_1755 | HMPREF9154_0416 | 5'-nucleotidase, C-terminal domain protein; Belongs to the 5'-nucleotidase family. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.902 |
AFN45375.1 | pyrF | HMPREF9154_1755 | HMPREF9154_1622 | 5'-nucleotidase, C-terminal domain protein; Belongs to the 5'-nucleotidase family. | Orotidine 5'-phosphate decarboxylase. | 0.902 |
apt | AFN45147.1 | HMPREF9154_1647 | HMPREF9154_0296 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-nucleotidase. | 0.900 |
apt | AFN45375.1 | HMPREF9154_1647 | HMPREF9154_1755 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-nucleotidase, C-terminal domain protein; Belongs to the 5'-nucleotidase family. | 0.936 |
apt | gmk | HMPREF9154_1647 | HMPREF9154_1620 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.974 |
apt | guaA | HMPREF9154_1647 | HMPREF9154_2130 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (glutamine-hydrolyzing), C-terminal domain protein; Catalyzes the synthesis of GMP from XMP. | 0.998 |