node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFN46588.1 | apt | HMPREF9154_1654 | HMPREF9154_1647 | DNA-binding regulatory protein, YebC/PmpR family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.695 |
AFN46588.1 | aspS | HMPREF9154_1654 | HMPREF9154_1640 | DNA-binding regulatory protein, YebC/PmpR family. | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | 0.797 |
AFN46588.1 | hisA | HMPREF9154_1654 | HMPREF9154_1659 | DNA-binding regulatory protein, YebC/PmpR family. | Bifunctional HisA/TrpF protein. | 0.712 |
AFN46588.1 | ruvA | HMPREF9154_1654 | HMPREF9154_1652 | DNA-binding regulatory protein, YebC/PmpR family. | Holliday junction DNA helicase RuvA, N-terminal domain protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.851 |
AFN46588.1 | ruvB | HMPREF9154_1654 | HMPREF9154_1651 | DNA-binding regulatory protein, YebC/PmpR family. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.857 |
AFN46588.1 | ruvC | HMPREF9154_1654 | HMPREF9154_1653 | DNA-binding regulatory protein, YebC/PmpR family. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.887 |
AFN46588.1 | secD | HMPREF9154_1654 | HMPREF9154_1649 | DNA-binding regulatory protein, YebC/PmpR family. | Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.739 |
AFN46588.1 | secF | HMPREF9154_1654 | HMPREF9154_1648 | DNA-binding regulatory protein, YebC/PmpR family. | Export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.737 |
AFN46588.1 | tyrS | HMPREF9154_1654 | HMPREF9154_2023 | DNA-binding regulatory protein, YebC/PmpR family. | tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.775 |
AFN46588.1 | yajC | HMPREF9154_1654 | HMPREF9154_1650 | DNA-binding regulatory protein, YebC/PmpR family. | Preprotein translocase, YajC subunit. | 0.754 |
apt | AFN46588.1 | HMPREF9154_1647 | HMPREF9154_1654 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | DNA-binding regulatory protein, YebC/PmpR family. | 0.695 |
apt | hisA | HMPREF9154_1647 | HMPREF9154_1659 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Bifunctional HisA/TrpF protein. | 0.488 |
apt | ruvA | HMPREF9154_1647 | HMPREF9154_1652 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Holliday junction DNA helicase RuvA, N-terminal domain protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.713 |
apt | ruvB | HMPREF9154_1647 | HMPREF9154_1651 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.720 |
apt | ruvC | HMPREF9154_1647 | HMPREF9154_1653 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.713 |
apt | secD | HMPREF9154_1647 | HMPREF9154_1649 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.896 |
apt | secF | HMPREF9154_1647 | HMPREF9154_1648 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.877 |
apt | yajC | HMPREF9154_1647 | HMPREF9154_1650 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Preprotein translocase, YajC subunit. | 0.826 |
aspS | AFN46588.1 | HMPREF9154_1640 | HMPREF9154_1654 | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | DNA-binding regulatory protein, YebC/PmpR family. | 0.797 |
aspS | tyrS | HMPREF9154_1640 | HMPREF9154_2023 | aspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.699 |