node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFN45217.1 | AFN45835.1 | HMPREF9154_1686 | HMPREF9154_1685 | Transcriptional regulator, PadR family. | Hypothetical protein. | 0.806 |
AFN45217.1 | hisI | HMPREF9154_1686 | HMPREF9154_1684 | Transcriptional regulator, PadR family. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.468 |
AFN45217.1 | trpC | HMPREF9154_1686 | HMPREF9154_1682 | Transcriptional regulator, PadR family. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.468 |
AFN45217.1 | trpE | HMPREF9154_1686 | HMPREF9154_1683 | Transcriptional regulator, PadR family. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.468 |
AFN45835.1 | AFN45217.1 | HMPREF9154_1685 | HMPREF9154_1686 | Hypothetical protein. | Transcriptional regulator, PadR family. | 0.806 |
AFN45835.1 | hisI | HMPREF9154_1685 | HMPREF9154_1684 | Hypothetical protein. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.468 |
AFN45835.1 | trpC | HMPREF9154_1685 | HMPREF9154_1682 | Hypothetical protein. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.468 |
AFN45835.1 | trpE | HMPREF9154_1685 | HMPREF9154_1683 | Hypothetical protein. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.468 |
hisI | AFN45217.1 | HMPREF9154_1684 | HMPREF9154_1686 | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | Transcriptional regulator, PadR family. | 0.468 |
hisI | AFN45835.1 | HMPREF9154_1684 | HMPREF9154_1685 | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | Hypothetical protein. | 0.468 |
hisI | trpC | HMPREF9154_1684 | HMPREF9154_1682 | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.860 |
hisI | trpE | HMPREF9154_1684 | HMPREF9154_1683 | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.960 |
trpC | AFN45217.1 | HMPREF9154_1682 | HMPREF9154_1686 | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | Transcriptional regulator, PadR family. | 0.468 |
trpC | AFN45835.1 | HMPREF9154_1682 | HMPREF9154_1685 | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | Hypothetical protein. | 0.468 |
trpC | hisI | HMPREF9154_1682 | HMPREF9154_1684 | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.860 |
trpC | trpE | HMPREF9154_1682 | HMPREF9154_1683 | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.999 |
trpE | AFN45217.1 | HMPREF9154_1683 | HMPREF9154_1686 | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | Transcriptional regulator, PadR family. | 0.468 |
trpE | AFN45835.1 | HMPREF9154_1683 | HMPREF9154_1685 | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | Hypothetical protein. | 0.468 |
trpE | hisI | HMPREF9154_1683 | HMPREF9154_1684 | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.960 |
trpE | trpC | HMPREF9154_1683 | HMPREF9154_1682 | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.999 |