STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde-2,1-aminomutase. (439 aa)    
Predicted Functional Partners:
hemB
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.999
hemA
glutamyl-tRNAGlu reductase, N-terminal domain protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.999
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.993
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.980
AFN47624.1
Beta-ketoacyl synthase, N-terminal domain protein.
 
  
 0.969
AFN46301.1
Porphobilinogen deaminase, dipyromethane cofactor-binding domain protein.
 
  
 0.958
AFN46682.1
Putative D-alanine--poly(phosphoribitol) ligase, subunit 1; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.942
AFN46611.1
Thi4 domain protein.
 
  
 0.924
AFN47463.1
KR domain protein.
 
  
 0.917
AFN46408.1
Putative bacitracin synthetase 1; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.879
Your Current Organism:
Pseudopropionibacterium propionicum
NCBI taxonomy Id: 767029
Other names: P. propionicum F0230a, Propionibacterium propionicum F0230a, Pseudopropionibacterium propionicum F0230a
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