node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFN46357.1 | ddl | HMPREF9154_1918 | HMPREF9154_1362 | POTRA domain protein, FtsQ-type; Essential cell division protein. | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.775 |
AFN46357.1 | ddl-2 | HMPREF9154_1918 | HMPREF9154_3181 | POTRA domain protein, FtsQ-type; Essential cell division protein. | D-ala D-ala ligase N-terminal-like domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.717 |
AFN46357.1 | ftsW | HMPREF9154_1918 | HMPREF9154_1921 | POTRA domain protein, FtsQ-type; Essential cell division protein. | Cell division protein FtsW; Belongs to the SEDS family. | 0.992 |
AFN46357.1 | mraY | HMPREF9154_1918 | HMPREF9154_1923 | POTRA domain protein, FtsQ-type; Essential cell division protein. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.917 |
AFN46357.1 | murC | HMPREF9154_1918 | HMPREF9154_1919 | POTRA domain protein, FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.993 |
AFN46357.1 | murD | HMPREF9154_1918 | HMPREF9154_1922 | POTRA domain protein, FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.982 |
AFN46357.1 | murE | HMPREF9154_1918 | HMPREF9154_1925 | POTRA domain protein, FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.946 |
AFN46357.1 | murF | HMPREF9154_1918 | HMPREF9154_1924 | POTRA domain protein, FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.972 |
AFN46357.1 | murG | HMPREF9154_1918 | HMPREF9154_1920 | POTRA domain protein, FtsQ-type; Essential cell division protein. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.994 |
alr | ddl | HMPREF9154_0329 | HMPREF9154_1362 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.993 |
alr | ddl-2 | HMPREF9154_0329 | HMPREF9154_3181 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | D-ala D-ala ligase N-terminal-like domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.947 |
alr | ftsW | HMPREF9154_0329 | HMPREF9154_1921 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Cell division protein FtsW; Belongs to the SEDS family. | 0.452 |
alr | mraY | HMPREF9154_0329 | HMPREF9154_1923 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.530 |
alr | murC | HMPREF9154_0329 | HMPREF9154_1919 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.560 |
alr | murD | HMPREF9154_0329 | HMPREF9154_1922 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.553 |
alr | murE | HMPREF9154_0329 | HMPREF9154_1925 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.595 |
alr | murF | HMPREF9154_0329 | HMPREF9154_1924 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.982 |
alr | murG | HMPREF9154_0329 | HMPREF9154_1920 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.635 |
ddl | AFN46357.1 | HMPREF9154_1362 | HMPREF9154_1918 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | POTRA domain protein, FtsQ-type; Essential cell division protein. | 0.775 |
ddl | alr | HMPREF9154_1362 | HMPREF9154_0329 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.993 |