| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFN44982.1 | AFN46907.1 | HMPREF9154_1209 | HMPREF9154_2617 | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | 0.928 |
| AFN44982.1 | carB | HMPREF9154_1209 | HMPREF9154_1624 | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.920 |
| AFN44982.1 | glmS | HMPREF9154_1209 | HMPREF9154_2174 | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.951 |
| AFN44982.1 | glnA | HMPREF9154_1209 | HMPREF9154_1223 | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | Glutamine synthetase, type I. | 0.920 |
| AFN46907.1 | AFN44982.1 | HMPREF9154_2617 | HMPREF9154_1209 | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | 0.928 |
| AFN46907.1 | carB | HMPREF9154_2617 | HMPREF9154_1624 | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.920 |
| AFN46907.1 | glmS | HMPREF9154_2617 | HMPREF9154_2174 | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.936 |
| AFN46907.1 | glnA | HMPREF9154_2617 | HMPREF9154_1223 | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | Glutamine synthetase, type I. | 0.926 |
| carB | AFN44982.1 | HMPREF9154_1624 | HMPREF9154_1209 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | 0.920 |
| carB | AFN46907.1 | HMPREF9154_1624 | HMPREF9154_2617 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | 0.920 |
| carB | glmS | HMPREF9154_1624 | HMPREF9154_2174 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.929 |
| carB | glnA | HMPREF9154_1624 | HMPREF9154_1223 | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | Glutamine synthetase, type I. | 0.920 |
| glmM | glmS | HMPREF9154_2177 | HMPREF9154_2174 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.982 |
| glmM | glmU | HMPREF9154_2177 | HMPREF9154_0567 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.996 |
| glmM | nagA | HMPREF9154_2177 | HMPREF9154_0746 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | N-acetylglucosamine-6-phosphate deacetylase. | 0.945 |
| glmM | nagB | HMPREF9154_2177 | HMPREF9154_0734 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine-6-phosphate deaminase. | 0.954 |
| glmM | pgi | HMPREF9154_2177 | HMPREF9154_2541 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.458 |
| glmS | AFN44982.1 | HMPREF9154_2174 | HMPREF9154_1209 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | 0.951 |
| glmS | AFN46907.1 | HMPREF9154_2174 | HMPREF9154_2617 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glutamine ligase, beta-grasp domain protein; Belongs to the glutamine synthetase family. | 0.936 |
| glmS | carB | HMPREF9154_2174 | HMPREF9154_1624 | Glutamine-fructose-6-phosphate transaminase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.929 |