STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFN46360.1Putative (2,3-dihydroxybenzoyl)adenylate synthase. (654 aa)    
Predicted Functional Partners:
AFN47624.1
Beta-ketoacyl synthase, N-terminal domain protein.
  
 0.999
AFN45636.1
Putative isochorismate synthase.
  
 0.999
AFN45546.1
Nonribosomal peptide synthase.
 
0.999
AFN46007.1
Nonribosomal peptide synthase.
  
0.999
AFN47463.1
KR domain protein.
 
 0.997
AFN46682.1
Putative D-alanine--poly(phosphoribitol) ligase, subunit 1; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.995
AFN46699.1
Condensation domain protein.
 
  
 0.993
AFN46245.1
Oxidoreductase, NAD-binding domain protein.
 
  
 0.988
AFN46408.1
Putative bacitracin synthetase 1; Belongs to the ATP-dependent AMP-binding enzyme family.
  
0.988
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
  
 0.983
Your Current Organism:
Pseudopropionibacterium propionicum
NCBI taxonomy Id: 767029
Other names: P. propionicum F0230a, Propionibacterium propionicum F0230a, Pseudopropionibacterium propionicum F0230a
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