AFN45175.1 protein (Pseudopropionibacterium propionicum)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

AFN45175.1

Periplasmic-binding protein. (367 aa)

Predicted Functional Partners:

AFN47222.1

0.950

AFN46407.1

0.902

AFN46173.1

0.818

AFN45320.1

0.799

AFN47562.1

0.777

AFN46845.1

0.733

AFN46388.1

0.690

AFN44907.1

0.661

AFN45182.1

0.548

AFN45979.1

0.543

Your Current Organism:

Pseudopropionibacterium propionicum

NCBI taxonomy Id: 767029
Other names: P. propionicum F0230a, Propionibacterium propionicum F0230a, Pseudopropionibacterium propionicum F0230a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFN44907.1	AFN45175.1	HMPREF9154_0114	HMPREF9154_2877	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	Periplasmic-binding protein.	0.661
AFN44907.1	AFN45320.1	HMPREF9154_0114	HMPREF9154_2873	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.738
AFN44907.1	AFN45979.1	HMPREF9154_0114	HMPREF9154_0812	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.640
AFN44907.1	AFN46173.1	HMPREF9154_0114	HMPREF9154_0115	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.945
AFN44907.1	AFN46388.1	HMPREF9154_0114	HMPREF9154_1272	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.718
AFN44907.1	AFN47222.1	HMPREF9154_0114	HMPREF9154_2878	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.782
AFN45175.1	AFN44907.1	HMPREF9154_2877	HMPREF9154_0114	Periplasmic-binding protein.	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	0.661
AFN45175.1	AFN45182.1	HMPREF9154_2877	HMPREF9154_0813	Periplasmic-binding protein.	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	0.548
AFN45175.1	AFN45320.1	HMPREF9154_2877	HMPREF9154_2873	Periplasmic-binding protein.	Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.799
AFN45175.1	AFN45979.1	HMPREF9154_2877	HMPREF9154_0812	Periplasmic-binding protein.	Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.543
AFN45175.1	AFN46173.1	HMPREF9154_2877	HMPREF9154_0115	Periplasmic-binding protein.	Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.818
AFN45175.1	AFN46388.1	HMPREF9154_2877	HMPREF9154_1272	Periplasmic-binding protein.	Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.690
AFN45175.1	AFN46407.1	HMPREF9154_2877	HMPREF9154_2879	Periplasmic-binding protein.	Putative ferrichrome ABC transporter, ATP-binding protein FhuC.	0.902
AFN45175.1	AFN46845.1	HMPREF9154_2877	HMPREF9154_1275	Periplasmic-binding protein.	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	0.733
AFN45175.1	AFN47222.1	HMPREF9154_2877	HMPREF9154_2878	Periplasmic-binding protein.	Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.950
AFN45175.1	AFN47562.1	HMPREF9154_2877	HMPREF9154_2872	Periplasmic-binding protein.	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	0.777
AFN45182.1	AFN45175.1	HMPREF9154_0813	HMPREF9154_2877	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	Periplasmic-binding protein.	0.548
AFN45182.1	AFN45320.1	HMPREF9154_0813	HMPREF9154_2873	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.571
AFN45182.1	AFN45979.1	HMPREF9154_0813	HMPREF9154_0812	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.942
AFN45182.1	AFN46173.1	HMPREF9154_0813	HMPREF9154_0115	Putative iron(III) dicitrate ABC transporter, ATP-binding protein FecE.	Iron chelate uptake ABC transporter, FeCT family, permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.	0.567

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Network Stats

number of nodes:

11

number of edges:

44

average node degree:

8

avg. local clustering coefficient:

0.825

expected number of edges:

10

PPI enrichment p-value:

9.21e-15

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009058

Biosynthetic process

9 of 320

0.57

0.35

0.0380

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 482

0.48

0.4

0.00045

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:993

Peptidoglycan synthesis, and Cell division site

4 of 18

1.47

1.08

0.0035

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00473

D-Alanine metabolism

4 of 4

2.12

2.46

1.11e-05

map01502

Vancomycin resistance

3 of 6

1.82

1.42

0.0012

map00290

Valine, leucine and isoleucine biosynthesis

2 of 2

2.12

1.14

0.0071

map01210

2-Oxocarboxylic acid metabolism

2 of 5

1.72

0.89

0.0174

map00550

Peptidoglycan biosynthesis

3 of 25

1.2

0.72

0.0174

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0573

Peptidoglycan synthesis

3 of 12

1.52

0.8

0.0214

KW-0961

Cell wall biogenesis/degradation

3 of 13

1.48

0.79

0.0214

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