node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EGL38427.1 | EGL38618.1 | HMPREF9126_0029 | HMPREF9126_0028 | Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Hypothetical protein; Displays ATPase and GTPase activities. | 0.968 |
EGL38427.1 | EGL38863.1 | HMPREF9126_0029 | HMPREF9126_0024 | Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. | 0.693 |
EGL38427.1 | hprK | HMPREF9126_0029 | HMPREF9126_0026 | Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.789 |
EGL38427.1 | murB | HMPREF9126_0029 | HMPREF9126_0027 | Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.835 |
EGL38427.1 | uvrC | HMPREF9126_0029 | HMPREF9126_0025 | Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.781 |
EGL38618.1 | EGL38427.1 | HMPREF9126_0028 | HMPREF9126_0029 | Hypothetical protein; Displays ATPase and GTPase activities. | Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.968 |
EGL38618.1 | EGL38863.1 | HMPREF9126_0028 | HMPREF9126_0024 | Hypothetical protein; Displays ATPase and GTPase activities. | Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. | 0.614 |
EGL38618.1 | hprK | HMPREF9126_0028 | HMPREF9126_0026 | Hypothetical protein; Displays ATPase and GTPase activities. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.784 |
EGL38618.1 | murB | HMPREF9126_0028 | HMPREF9126_0027 | Hypothetical protein; Displays ATPase and GTPase activities. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.846 |
EGL38618.1 | uvrC | HMPREF9126_0028 | HMPREF9126_0025 | Hypothetical protein; Displays ATPase and GTPase activities. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.781 |
EGL38729.1 | dnaN | HMPREF9126_0510 | HMPREF9126_1490 | Exonuclease, DNA polymerase III, epsilon subunit family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.512 |
EGL38729.1 | polA | HMPREF9126_0510 | HMPREF9126_0429 | Exonuclease, DNA polymerase III, epsilon subunit family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.576 |
EGL38729.1 | uvrC | HMPREF9126_0510 | HMPREF9126_0025 | Exonuclease, DNA polymerase III, epsilon subunit family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.948 |
EGL38863.1 | EGL38427.1 | HMPREF9126_0024 | HMPREF9126_0029 | Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. | Hypothetical protein; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.693 |
EGL38863.1 | EGL38618.1 | HMPREF9126_0024 | HMPREF9126_0028 | Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. | Hypothetical protein; Displays ATPase and GTPase activities. | 0.614 |
EGL38863.1 | hprK | HMPREF9126_0024 | HMPREF9126_0026 | Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] | 0.720 |
EGL38863.1 | murB | HMPREF9126_0024 | HMPREF9126_0027 | Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.604 |
EGL38863.1 | polA | HMPREF9126_0024 | HMPREF9126_0429 | Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.619 |
EGL38863.1 | uvrC | HMPREF9126_0024 | HMPREF9126_0025 | Creatinase; Identified by match to protein family HMM PF00557; match to protein family HMM PF01321. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.720 |
dnaN | EGL38729.1 | HMPREF9126_1490 | HMPREF9126_0510 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exonuclease, DNA polymerase III, epsilon subunit family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. | 0.512 |