Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KRV51303.13D-(3,5/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (625 aa)    
Predicted Functional Partners:
KRV51302.1
5-deoxy-glucuronate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
KRV51509.1
Inosose dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.993
KRV51300.1
5-dehydro-2-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.973
KRV51301.1
Deoxyribose-phosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.932
KRV51299.1
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.910
KRV51298.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.868
KRV51290.1
Sugar ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.849
KRV51288.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.832
KRV51289.1
Ribose ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family.
 
    0.820
KRV51185.1
Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.725
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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