Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KRV49332.13-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA glycosylase MPG family. (224 aa)    
Predicted Functional Partners:
KRV49331.1
Sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.726
KRV49330.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.658
tyrS
tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
     
 0.605
KRV49359.1
HNH nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.588
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
   
  
 0.543
cysS
cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.535
KRV51335.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.530
KRV51508.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.515
pheT
phenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
    0.505
AQ490_03070
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.424
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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