Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KRV48459.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)    
Predicted Functional Partners:
KRV48455.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.617
KRV49385.1
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.602
KRV47068.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.592
KRV46531.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.563
KRV48722.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.531
KRV51375.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.513
KRV49431.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.511
purM
Phosphoribosylaminoimidazole synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.499
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
       0.499
purL
Phosphoribosylglycinamide synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the tr [...]
       0.499
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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