STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRV47678.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.915
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
 
 0.907
KRV47907.1
Phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.761
KRV47911.1
Long-chain acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.727
KRV49720.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.722
KRV48876.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.652
KRV46420.1
Coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.647
KRV47677.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.632
KRV50654.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.614
KRV50697.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.614
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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