Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KRV47719.14-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)    
Predicted Functional Partners:
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
 0.995
KRV49769.1
Fumarylacetoacetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.916
pat
Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
    
 0.881
AQ490_00175
Aminotran_1_2 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.875
KRV49144.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.875
hisC
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
    
 0.873
KRV49680.1
Amidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the amidase family.
   
 
  0.873
KRV50207.1
Aminotransferase class I/II; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.872
AQ490_21390
Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.817
KRV50827.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.797
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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