Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KRV47916.1FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)    
Predicted Functional Partners:
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.890
KRV51312.1
Malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the malate synthase family.
  
 
 0.884
KRV46408.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.880
KRV46607.1
Keto-deoxy-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.874
KRV46716.1
Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.873
AQ490_00260
Citrate (Pro-3S)-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family.
     
  0.870
KRV47592.1
Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.870
KRV50073.1
Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.870
KRV50477.1
2-hydroxy-acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.841
AQ490_03070
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.715
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
Server load: low (38%) [HD]