Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AQ490_06150Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)    
Predicted Functional Partners:
vapC
Ribonuclease; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
   0.763
KRV49461.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.704
disA
DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
     0.669
KRV46895.1
Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.581
KRV49385.1
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.567
KRV47335.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.490
KRV51366.1
Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.471
KRV47949.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.458
KRV47948.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.443
AQ490_22720
Coenzyme F420 biosynthesis-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.441
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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