Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KRV47522.1Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (608 aa)    
Predicted Functional Partners:
KRV51492.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.975
KRV51151.1
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.852
KRV47521.1
3-hydroxybutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.835
KRV47523.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.664
KRV49374.1
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.648
KRV50245.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
  0.645
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
  0.645
KRV49199.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.565
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
    
  0.531
KRV48979.1
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.525
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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