Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KRV46383.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)    
Predicted Functional Partners:
KRV46382.1
Dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family.
  
  
 0.859
KRV46386.1
Rod shape-determining protein MreD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.811
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.775
KRV51434.1
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.764
valS
valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
     
 0.762
KRV50284.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.750
KRV46387.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.692
KRV48724.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.685
KRV46385.1
Rod shape-determining protein MreC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.676
KRV50929.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.629
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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