Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KRV46434.1Peptidase M4; Extracellular zinc metalloprotease. (372 aa)    
Predicted Functional Partners:
KRV46433.1
Metalloprotease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.794
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
       0.653
AQ490_18990
Peptidase M28; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.600
KRV46436.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.595
KRV50544.1
Chitin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.453
KRV49234.1
Peptidase M14; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.448
KRV51492.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.408
tam
Trans-aconitate methyltransferase; Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
  
     0.408
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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