Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
KRV50852.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)    
Predicted Functional Partners:
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
     
  0.732
katE
Hydroperoxidase; Serves to protect cells from the toxic effects of hydrogen peroxide.
    
  0.695
KRV51418.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.677
KRV51492.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.649
KRV48792.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.568
menG
Ubiquinone biosynthesis methyltransferase UbiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
  
    0.558
KRV48789.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.554
KRV49779.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.551
KRV49111.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.548
KRV46670.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.527
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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