Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KRV50714.1N-6 DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)    
Predicted Functional Partners:
KRV50224.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.706
KRV50223.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.653
KRV50214.1
AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.642
KRV50222.1
Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.631
KRV50213.1
Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.622
KRV50780.1
Phenazine biosynthesis protein PhzA/PhzB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.609
KRV50212.1
DNA helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.591
KRV50779.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.557
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
   0.539
KRV47367.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.474
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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