Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KRV50240.1Carboxylate--amine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)    
Predicted Functional Partners:
KRV50241.1
Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.684
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
     0.670
KRV50245.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.582
KRV50244.1
IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.499
KRV48304.1
Fuconate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
       0.499
KRV48307.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.499
KRV51371.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.491
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
       0.471
KRV49899.1
Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.442
KRV47641.1
NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.440
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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