Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KRV50367.1AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)    
Predicted Functional Partners:
KRV47322.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.822
KRV47106.1
ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.797
KRV50597.1
ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.787
KRV49023.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.774
KRV50366.1
Vitamin K epoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.758
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
     
 0.731
KRV51448.1
Recombinase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.724
KRV50361.1
DNA repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.722
KRV51134.1
Macro domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.708
KRV50362.1
Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.679
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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