Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KRV50744.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)    
Predicted Functional Partners:
KRV50512.1
Trehalose 6-phosphate phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.996
KRV49246.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.879
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
 
  0.750
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.639
KRV48432.1
Dimethylmenaquinone methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.547
KRV50051.1
Dimethylmenaquinone methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.542
KRV49144.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.507
KRV50537.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.499
KRV50756.1
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family.
    
  0.487
AQ490_21390
Uncharacterized protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.484
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.