Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KRV50117.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)    
Predicted Functional Partners:
KRV50116.1
5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.
     
 0.829
KRV48508.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.772
KRV49441.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.719
KRV50046.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.714
KRV51332.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.707
KRV51361.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.678
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
       0.676
KRV49292.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.670
KRV46603.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.646
KRV50113.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.634
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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