Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KRV49986.1Transcription initiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)    
Predicted Functional Partners:
KRV49987.1
RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family.
 
     0.951
KRV50402.1
RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family.
 
     0.736
KRV49988.1
Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.639
KRV46834.1
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.499
tsaD
tRNA N6-adenosine threonylcarbamoyltransferase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
       0.499
KRV46836.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.499
KRV49475.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.499
KRV49985.1
acyl-ACP desaturase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.476
KRV46989.1
Erythropoiesis-stimulating protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.416
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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