Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepAAminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (510 aa)    
Predicted Functional Partners:
KRV49208.1
Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.905
KRV46360.1
Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.905
KRV46362.1
Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.905
AQ490_00175
Aminotran_1_2 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.888
KRV47439.1
Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.885
KRV47271.1
Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.871
KRV49764.1
Carboxylate--amine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.870
egtA
Ergothioneine biosynthesis glutamate--cysteine ligase EgtA; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
     
  0.870
KRV48760.1
Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.779
KRV46487.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.778
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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