Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KRV49831.1Acyl-peptide hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (668 aa)    
Predicted Functional Partners:
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
     
  0.692
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.659
KRV51239.1
Peptide ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.628
KRV48685.1
PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.567
KRV51240.1
Polyketide cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.561
KRV49830.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.521
KRV51502.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.499
KRV51238.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.499
KRV50997.1
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.499
KRV47872.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.499
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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