Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KRV49402.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)    
Predicted Functional Partners:
KRV49186.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.718
egtD
Histidine N-alpha-methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
  
 
 0.673
KRV48560.1
Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.611
KRV49144.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.587
KRV48639.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.557
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.536
KRV47979.1
Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.485
KRV49484.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.455
KRV49044.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.427
KRV49501.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.408
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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