Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
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[Homology]
Score
cutCCopper homeostasis protein CutC; Participates in the control of copper homeostasis. Belongs to the CutC family. (256 aa)    
Predicted Functional Partners:
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
   0.702
KRV49074.1
Microcystin degradation protein MlrC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.656
KRV49406.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.655
KRV47706.1
beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.630
KRV48308.1
alpha-L-fucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.573
KRV46907.1
beta-N-acetylglucosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.546
KRV46550.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.525
KRV47874.1
Glycoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.499
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
    0.494
KRV48260.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.440
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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