Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KRV48850.1UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (335 aa)    
Predicted Functional Partners:
KRV48851.1
Galactose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.999
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily.
 
 0.991
KRV50006.1
UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.932
KRV47947.1
Mannose-1-phosphate guanyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.919
KRV48746.1
UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.912
glmU
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
   
 0.909
KRV48731.1
GDP-mannose pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.884
fcl
GDP-fucose synthetase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
    
 0.872
KRV50927.1
NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.872
KRV48045.1
UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.870
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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