Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KRV48876.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1405 aa)    
Predicted Functional Partners:
KRV51168.1
Trehalose phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
    0.779
KRV47738.1
dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
   0.744
KRV50333.1
Disulfide bond formation protein DsbA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.719
nhaA
Sodium:proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
   
    0.708
KRV48875.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.697
KRV47678.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.652
KRV46827.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.631
KRV48003.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.591
KRV46937.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.548
KRV48427.1
Transmembrane transport protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.536
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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