Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KRV48537.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (848 aa)    
Predicted Functional Partners:
KRV48548.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
KRV51492.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.992
kdpC
Potassium-transporting ATPase subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
 
  
 0.987
kdpB
Potassium transporter KtrB; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
 
  
 0.969
kdpA
Potassium-transporting ATPase subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane.
 
  
 0.960
KRV51151.1
Protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.930
KRV47038.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.626
KRV48090.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.626
KRV48523.1
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.531
AQ490_07385
Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.528
Your Current Organism:
Streptomyces vitaminophilus
NCBI taxonomy Id: 76728
Other names: ATCC 31673, Actinosporangium vitaminiphilum, Actinosporangium vitaminophilum, DSM 41686, IFO 14294, JCM 6054, NBRC 14294, NRRL B-16933, S. vitaminophilus, Streptomyces vitaminiphilus, Streptomyces vitaminophileus, strain SF 2080
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