| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALV06007.1 | ALV07442.1 | RD2015_1522 | RD2015_2980 | PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | 0.656 |
| ALV07442.1 | ALV06007.1 | RD2015_2980 | RD2015_1522 | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | PEP synthetase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. | 0.656 |
| ALV07442.1 | ALV07443.1 | RD2015_2980 | RD2015_2981 | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.498 |
| ALV07442.1 | ALV07444.1 | RD2015_2980 | RD2015_2982 | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | Pfam:pfam12697 Alpha/beta hydrolase family. | 0.495 |
| ALV07442.1 | ALV08348.1 | RD2015_2980 | RD2015_3897 | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | Pfam:pfam09361 Phasin protein. | 0.435 |
| ALV07442.1 | ALV09262.1 | RD2015_2980 | RD2015_4827 | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | 3-deoxy-manno-octulosonate-8-phosphatase. | 0.438 |
| ALV07442.1 | aroC | RD2015_2980 | RD2015_2979 | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.473 |
| ALV07442.1 | guaA | RD2015_2980 | RD2015_3356 | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.457 |
| ALV07443.1 | ALV07442.1 | RD2015_2981 | RD2015_2980 | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | 0.498 |
| ALV07443.1 | ALV07444.1 | RD2015_2981 | RD2015_2982 | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | Pfam:pfam12697 Alpha/beta hydrolase family. | 0.791 |
| ALV07444.1 | ALV07442.1 | RD2015_2982 | RD2015_2980 | Pfam:pfam12697 Alpha/beta hydrolase family. | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | 0.495 |
| ALV07444.1 | ALV07443.1 | RD2015_2982 | RD2015_2981 | Pfam:pfam12697 Alpha/beta hydrolase family. | O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme. | 0.791 |
| ALV07444.1 | aroC | RD2015_2982 | RD2015_2979 | Pfam:pfam12697 Alpha/beta hydrolase family. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.406 |
| ALV08348.1 | ALV07442.1 | RD2015_3897 | RD2015_2980 | Pfam:pfam09361 Phasin protein. | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | 0.435 |
| ALV09262.1 | ALV07442.1 | RD2015_4827 | RD2015_2980 | 3-deoxy-manno-octulosonate-8-phosphatase. | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | 0.438 |
| aroC | ALV07442.1 | RD2015_2979 | RD2015_2980 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | 0.473 |
| aroC | ALV07444.1 | RD2015_2979 | RD2015_2982 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Pfam:pfam12697 Alpha/beta hydrolase family. | 0.406 |
| aroC | guaA | RD2015_2979 | RD2015_3356 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.582 |
| guaA | ALV07442.1 | RD2015_3356 | RD2015_2980 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | CBS domain-containing protein; Pfam:pfam00571 CBS domain. | 0.457 |
| guaA | aroC | RD2015_3356 | RD2015_2979 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.582 |