STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALV07499.1acetyl-CoA synthetase; Pfam:pfam00501 AMP-binding enzyme. (635 aa)    
Predicted Functional Partners:
ALV04714.1
Methylmalonic acid semialdehyde dehydrogenase; Pfam:pfam00171 Aldehyde dehydrogenase family.
  
 0.937
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.935
ALV06105.1
AMP-dependent synthetase and ligase; Pfam:pfam00501 AMP-binding enzyme.
  
  
 
0.926
ALV05327.1
Pfam:pfam00441 Acyl-CoA dehydrogenase, C-terminal domain.
  
 
 0.924
ALV06752.1
Pfam:pfam01039 Carboxyl transferase domain.
  
 0.918
ALV04655.1
Pfam:pfam01515 Phosphate acetyl/butaryl transferase.
  
 
 0.915
ALV06645.1
acetyl-CoA carboxylase; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain.
  
 0.914
ALV06753.1
Acetyl-CoA carboxylase; Pfam:pfam02786 Carbamoyl-phosphate synthase L chain, ATP binding domain.
  
 0.914
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 
0.910
ALV05684.1
acetyl-CoA acetyltransferase; Pfam:pfam00108 Thiolase, N-terminal domain; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.880
Your Current Organism:
Roseateles depolymerans
NCBI taxonomy Id: 76731
Other names: CCUG 52219, DSM 11813, R. depolymerans, proteobacterium DSM11813, proteobacterium DSM11814, strain 61A
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