STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALV04813.1Glyoxalase; Pfam:pfam12681 Glyoxalase-like domain. (128 aa)    
Predicted Functional Partners:
ALV08343.1
Lactate dehydrogenase-like oxidoreductase; Pfam:pfam00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
    
 0.906
gloB
Hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
     
 0.901
ALV09182.1
Beta-lactamase domain protein; Pfam:pfam00753 Metallo-beta-lactamase superfamily.
     
 0.901
ALV06754.1
Methylmalonyl-CoA epimerase; Pfam:pfam13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.
     
  0.900
ALV08999.1
Glyoxalase; Pfam:pfam00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.
     
  0.900
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
   
  0.817
ALV08733.1
Serine dehydratase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme.
   
 0.809
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 0.809
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
  0.800
ALV07429.1
L-serine ammonia-lyase; Pfam:pfam03313 Serine dehydratase alpha chain.
     
  0.800
Your Current Organism:
Roseateles depolymerans
NCBI taxonomy Id: 76731
Other names: CCUG 52219, DSM 11813, R. depolymerans, proteobacterium DSM11813, proteobacterium DSM11814, strain 61A
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