node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALV06382.1 | ALV06830.1 | RD2015_1903 | RD2015_2359 | Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.503 |
ALV06382.1 | ALV08045.1 | RD2015_1903 | RD2015_3589 | Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin biosynthesis protein RibF; Pfam:pfam06574 FAD synthetase; Belongs to the ribF family. | 0.732 |
ALV06382.1 | coaE | RD2015_1903 | RD2015_998 | Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.543 |
ALV06382.1 | gmk | RD2015_1903 | RD2015_3713 | Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.518 |
ALV06830.1 | ALV06382.1 | RD2015_2359 | RD2015_1903 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.503 |
ALV06830.1 | ALV07406.1 | RD2015_2359 | RD2015_2944 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin synthase alpha chain RibE; Pfam:pfam00677 Lumazine binding domain. | 0.996 |
ALV06830.1 | ALV08045.1 | RD2015_2359 | RD2015_3589 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin biosynthesis protein RibF; Pfam:pfam06574 FAD synthetase; Belongs to the ribF family. | 0.736 |
ALV06830.1 | ALV08402.1 | RD2015_2359 | RD2015_3952 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | HAD family hydrolase; Pfam:pfam13419 Haloacid dehalogenase-like hydrolase. | 0.939 |
ALV06830.1 | coaE | RD2015_2359 | RD2015_998 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.477 |
ALV06830.1 | gmk | RD2015_2359 | RD2015_3713 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.520 |
ALV06830.1 | ribH | RD2015_2359 | RD2015_2357 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.993 |
ALV06830.1 | ribH-2 | RD2015_2359 | RD2015_3332 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.981 |
ALV07406.1 | ALV06830.1 | RD2015_2944 | RD2015_2359 | Riboflavin synthase alpha chain RibE; Pfam:pfam00677 Lumazine binding domain. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.996 |
ALV07406.1 | ALV08045.1 | RD2015_2944 | RD2015_3589 | Riboflavin synthase alpha chain RibE; Pfam:pfam00677 Lumazine binding domain. | Riboflavin biosynthesis protein RibF; Pfam:pfam06574 FAD synthetase; Belongs to the ribF family. | 0.938 |
ALV07406.1 | ALV08402.1 | RD2015_2944 | RD2015_3952 | Riboflavin synthase alpha chain RibE; Pfam:pfam00677 Lumazine binding domain. | HAD family hydrolase; Pfam:pfam13419 Haloacid dehalogenase-like hydrolase. | 0.903 |
ALV07406.1 | ribH | RD2015_2944 | RD2015_2357 | Riboflavin synthase alpha chain RibE; Pfam:pfam00677 Lumazine binding domain. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.997 |
ALV07406.1 | ribH-2 | RD2015_2944 | RD2015_3332 | Riboflavin synthase alpha chain RibE; Pfam:pfam00677 Lumazine binding domain. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.997 |
ALV08045.1 | ALV06382.1 | RD2015_3589 | RD2015_1903 | Riboflavin biosynthesis protein RibF; Pfam:pfam06574 FAD synthetase; Belongs to the ribF family. | Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.732 |
ALV08045.1 | ALV06830.1 | RD2015_3589 | RD2015_2359 | Riboflavin biosynthesis protein RibF; Pfam:pfam06574 FAD synthetase; Belongs to the ribF family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.736 |
ALV08045.1 | ALV07406.1 | RD2015_3589 | RD2015_2944 | Riboflavin biosynthesis protein RibF; Pfam:pfam06574 FAD synthetase; Belongs to the ribF family. | Riboflavin synthase alpha chain RibE; Pfam:pfam00677 Lumazine binding domain. | 0.938 |