STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALV08150.1DNA mismatch repair protein MutS; Pfam:pfam01713 Smr domain. (213 aa)    
Predicted Functional Partners:
ALV08149.1
DNA repair protein; Pfam:pfam04002 RadC-like JAB domain; Belongs to the UPF0758 family.
       0.804
ALV08148.1
Pfam:pfam00254 FKBP-type peptidyl-prolyl cis-trans isomerase.
 
     0.693
rpmD
Pfam:pfam00327 Ribosomal protein L30p/L7e.
  
 
   0.651
ALV06338.1
30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
  
 
   0.646
rplX
50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
  
 
   0.636
rpsT
30S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
 
 
   0.632
rpmG
Pfam:pfam00471 Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
  
 
   0.630
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
   0.615
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
   
   0.614
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.608
Your Current Organism:
Roseateles depolymerans
NCBI taxonomy Id: 76731
Other names: CCUG 52219, DSM 11813, R. depolymerans, proteobacterium DSM11813, proteobacterium DSM11814, strain 61A
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