STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALV08252.1Molybdopterin biosynthesis protein MoeB; Pfam:pfam00899 ThiF family. (254 aa)    
Predicted Functional Partners:
ALV07489.1
Molybdopterin converting factor, small subunit; Pfam:pfam02597 ThiS family.
  
 0.982
ALV06146.1
Thiamine biosynthesis protein ThiS.
  
 0.973
ALV08808.1
Phosphomethylpyrimidine kinase / thiamine-phosphate pyrophosphorylase; Pfam:pfam08543 Phosphomethylpyrimidine kinase.
 
  
 0.970
ALV05156.1
Hypothetical protein; Pfam:pfam00266 Aminotransferase class-V.
   
 0.966
ALV07180.1
Pfam:pfam02391 MoaE protein.
 
 0.963
ALV08806.1
Sulfur transfer protein; Pfam:pfam02597 ThiS family.
  
 
 0.961
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
   
 0.954
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.944
ALV06578.1
Rhodanese-related sulfurtransferase; Pfam:pfam00581 Rhodanese-like domain.
    
 0.907
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.906
Your Current Organism:
Roseateles depolymerans
NCBI taxonomy Id: 76731
Other names: CCUG 52219, DSM 11813, R. depolymerans, proteobacterium DSM11813, proteobacterium DSM11814, strain 61A
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