STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RD2015_67Cystathionine beta-synthase; Pfam:pfam00291 Pyridoxal-phosphate dependent enzyme. (489 aa)    
Predicted Functional Partners:
RD2015_66
Cystathionine gamma-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme.
 
 0.998
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 0.992
ALV07821.1
Cystathionine beta-lyase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme.
 
 0.992
ALV06921.1
Serine O-acetyltransferase.
 
 0.952
ALV07292.1
Serine O-acetyltransferase.
 
 0.951
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.947
ALV07443.1
O-acetylhomoserine aminocarboxypropyltransferase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme.
 
 
 0.947
ALV08328.1
Serine acetyltransferase.
 
 0.947
ALV07946.1
Putative homocysteine synthase; Pfam:pfam01053 Cys/Met metabolizm PLP-dependent enzyme.
  
 
 0.940
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.938
Your Current Organism:
Roseateles depolymerans
NCBI taxonomy Id: 76731
Other names: CCUG 52219, DSM 11813, R. depolymerans, proteobacterium DSM11813, proteobacterium DSM11814, strain 61A
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