STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFR86924.1Replicative DNA helicase Mcm; Belongs to the MCM family. (1336 aa)    
Predicted Functional Partners:
priL
DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
  
 
 0.990
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
  
 0.976
SFR86015.1
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
 
 0.975
SFS10547.1
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
  
 0.975
SFR88410.1
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
  
 0.972
SFS09908.1
ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication.
   
 0.966
SFS10553.1
Cell division control protein 6; Involved in regulation of DNA replication.
   
 0.966
SFS01248.1
Replicative DNA polymerase I.
  
 0.965
SFS12803.1
DNA polymerase I.
  
 0.960
SFR97297.1
DNA polymerase I.
  
 0.959
Your Current Organism:
Halomicrobium zhouii
NCBI taxonomy Id: 767519
Other names: CGMCC 1.10457, H. zhouii, Halobacteriaceae archaeon TBN51, Halomicrobium zhouii Yang and Cui 2012, JCM 17095, strain TBN51
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.