Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rlmG50S rRNA methyltransferase; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (374 aa)    
Predicted Functional Partners:
AMA44709.1
ferredoxin--NADP(+) reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.921
AMA44708.1
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.841
AMA44246.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.671
AMA46459.1
50S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.665
mscL
Large-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
       0.645
AMA46722.1
Polyphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.535
AMA46129.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.434
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
     
 0.414
obgE
GTPase Obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
   
  
 0.413
nusG
Transcription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination.
  
  
 0.408
Your Current Organism:
Pseudomonas monteilii
NCBI taxonomy Id: 76759
Other names: ATCC 700476, CCUG 38736, CFML 90-60, CIP 104883, DSM 14164, JCM 21585, NBRC 103158, P. monteilii, Pseudomonas sp. MKP 213, Pseudomonas sp. V7SW2
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