Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMA44744.1DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)    
Predicted Functional Partners:
AMA44745.1
6-O-methylguanine DNA methyltransferase; Regulates genes involved in the repair of alkylated DNA; repairs DNA containing 6-O-methylguanine; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.952
AMA45662.1
Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
  
 0.915
AMA44177.1
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.815
AMA46295.1
Exonuclease III; Removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.815
AMA44743.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.781
AMA47673.1
DNA polymerase I; Has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.696
recA
DNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
   
 
 0.633
AMA47866.1
Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.591
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.567
AMA46009.1
DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.567
Your Current Organism:
Pseudomonas monteilii
NCBI taxonomy Id: 76759
Other names: ATCC 700476, CCUG 38736, CFML 90-60, CIP 104883, DSM 14164, JCM 21585, NBRC 103158, P. monteilii, Pseudomonas sp. MKP 213, Pseudomonas sp. V7SW2
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