| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMA44429.1 | AMA44799.1 | APT63_01680 | APT63_03760 | Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.410 |
| AMA44429.1 | AMA44869.1 | APT63_01680 | APT63_04145 | Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | AmpG family muropeptide MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.602 |
| AMA44429.1 | anmK | APT63_01680 | APT63_01810 | Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.687 |
| AMA44429.1 | mpl | APT63_01680 | APT63_02345 | Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.593 |
| AMA44429.1 | nagZ | APT63_01680 | APT63_07360 | Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.613 |
| AMA44799.1 | AMA44429.1 | APT63_03760 | APT63_01680 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.410 |
| AMA44799.1 | AMA44869.1 | APT63_03760 | APT63_04145 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | AmpG family muropeptide MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.708 |
| AMA44799.1 | anmK | APT63_03760 | APT63_01810 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.612 |
| AMA44799.1 | mpl | APT63_03760 | APT63_02345 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.768 |
| AMA44799.1 | nagZ | APT63_03760 | APT63_07360 | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.754 |
| AMA44869.1 | AMA44429.1 | APT63_04145 | APT63_01680 | AmpG family muropeptide MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.602 |
| AMA44869.1 | AMA44799.1 | APT63_04145 | APT63_03760 | AmpG family muropeptide MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.708 |
| AMA44869.1 | anmK | APT63_04145 | APT63_01810 | AmpG family muropeptide MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.694 |
| AMA44869.1 | mpl | APT63_04145 | APT63_02345 | AmpG family muropeptide MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.453 |
| AMA44869.1 | nagZ | APT63_04145 | APT63_07360 | AmpG family muropeptide MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.770 |
| AMA45170.1 | nagZ | APT63_05725 | APT63_07360 | Mechanosensitive ion channel protein MscS; Derived by automated computational analysis using gene prediction method: Protein Homology. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.880 |
| AMA45462.1 | AMA45464.1 | APT63_07345 | APT63_07355 | Cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.934 |
| AMA45462.1 | AMA45466.1 | APT63_07345 | APT63_07365 | Cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | 5-oxo-L-prolinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.476 |
| AMA45462.1 | lexA | APT63_07345 | APT63_07350 | Cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | LexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.981 |
| AMA45462.1 | nagZ | APT63_07345 | APT63_07360 | Cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. | Beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.914 |
