| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| djlA | dxs | HELO_1085 | HELO_1084 | K05801 DnaJ like chaperone protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.754 |
| djlA | ispA | HELO_1085 | HELO_1083 | K05801 DnaJ like chaperone protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | Geranylgeranyl pyrophosphate synthetase chloroplast precursor - Hevea brasiliensis (Para rubber tree),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | 0.743 |
| djlA | serA | HELO_1085 | HELO_1081 | K05801 DnaJ like chaperone protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | D-3-phosphoglycerate dehydrogenase; High confidence in function and specificity; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.652 |
| djlA | xseB | HELO_1085 | HELO_1082 | K05801 DnaJ like chaperone protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | Hypothetical protein predicted by Glimmer/Critica; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.743 |
| dxs | djlA | HELO_1084 | HELO_1085 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | K05801 DnaJ like chaperone protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 0.754 |
| dxs | ispA | HELO_1084 | HELO_1083 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Geranylgeranyl pyrophosphate synthetase chloroplast precursor - Hevea brasiliensis (Para rubber tree),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | 0.945 |
| dxs | serA | HELO_1084 | HELO_1081 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | D-3-phosphoglycerate dehydrogenase; High confidence in function and specificity; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.711 |
| dxs | xseB | HELO_1084 | HELO_1082 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Hypothetical protein predicted by Glimmer/Critica; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.890 |
| hemC | ispA | HELO_4255 | HELO_1083 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Geranylgeranyl pyrophosphate synthetase chloroplast precursor - Hevea brasiliensis (Para rubber tree),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | 0.418 |
| hemC | ispB | HELO_4255 | HELO_1309 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Octaprenyl-diphosphate synthase - Escherichia coli (strain K12),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | 0.448 |
| hemC | xseB | HELO_4255 | HELO_1082 | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | Hypothetical protein predicted by Glimmer/Critica; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.546 |
| ispA | djlA | HELO_1083 | HELO_1085 | Geranylgeranyl pyrophosphate synthetase chloroplast precursor - Hevea brasiliensis (Para rubber tree),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | K05801 DnaJ like chaperone protein; Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host. | 0.743 |
| ispA | dxs | HELO_1083 | HELO_1084 | Geranylgeranyl pyrophosphate synthetase chloroplast precursor - Hevea brasiliensis (Para rubber tree),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.945 |
| ispA | hemC | HELO_1083 | HELO_4255 | Geranylgeranyl pyrophosphate synthetase chloroplast precursor - Hevea brasiliensis (Para rubber tree),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.418 |
| ispA | ispB | HELO_1083 | HELO_1309 | Geranylgeranyl pyrophosphate synthetase chloroplast precursor - Hevea brasiliensis (Para rubber tree),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | Octaprenyl-diphosphate synthase - Escherichia coli (strain K12),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | 0.923 |
| ispA | serA | HELO_1083 | HELO_1081 | Geranylgeranyl pyrophosphate synthetase chloroplast precursor - Hevea brasiliensis (Para rubber tree),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | D-3-phosphoglycerate dehydrogenase; High confidence in function and specificity; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.727 |
| ispA | xseA | HELO_1083 | HELO_1621 | Geranylgeranyl pyrophosphate synthetase chloroplast precursor - Hevea brasiliensis (Para rubber tree),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.629 |
| ispA | xseB | HELO_1083 | HELO_1082 | Geranylgeranyl pyrophosphate synthetase chloroplast precursor - Hevea brasiliensis (Para rubber tree),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | Hypothetical protein predicted by Glimmer/Critica; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.935 |
| ispB | hemC | HELO_1309 | HELO_4255 | Octaprenyl-diphosphate synthase - Escherichia coli (strain K12),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.448 |
| ispB | ispA | HELO_1309 | HELO_1083 | Octaprenyl-diphosphate synthase - Escherichia coli (strain K12),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | Geranylgeranyl pyrophosphate synthetase chloroplast precursor - Hevea brasiliensis (Para rubber tree),InterPro: Polyprenyl synthetase, High confidence in function and specificity; Belongs to the FPP/GGPP synthase family. | 0.923 |