node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HELO_1141 | nadR | HELO_1141 | HELO_2550 | Hypothetical protein; tRNA pseudouridine synthase D - Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039),InterPro: Protein of unknown function YGGT, Hypothetical protein. | Bifunctional NMN adenylyltransferase/Nudix hydrolase [Includes: Nicotinamide-nucleotide adenylyltransferase -Synechocystis sp. (strain PCC 6803),InterPro: Cytidylyltransferase, High confidence in function and specificity. | 0.426 |
HELO_1141 | sIR2 | HELO_1141 | HELO_1142 | Hypothetical protein; tRNA pseudouridine synthase D - Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039),InterPro: Protein of unknown function YGGT, Hypothetical protein. | NAD-dependent deacetylase; High confidence in function and specificity. | 0.777 |
HELO_4099 | ldh | HELO_4099 | HELO_2552 | Cytochrome P450; Fatty acid synthase - Bos taurus (Bovine),InterPro: Cytochrome P450, High confidence in function and specificity. | Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Leucine dehydrogenase - Bacillus stearothermophilus (Geobacillus stearothermophilus),InterPro: Glu/Leu/Phe/Val dehydrogenase C terminal, Specificity unclear; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.403 |
HELO_4099 | nadE | HELO_4099 | HELO_1328 | Cytochrome P450; Fatty acid synthase - Bos taurus (Bovine),InterPro: Cytochrome P450, High confidence in function and specificity. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.518 |
HELO_4099 | sIR2 | HELO_4099 | HELO_1142 | Cytochrome P450; Fatty acid synthase - Bos taurus (Bovine),InterPro: Cytochrome P450, High confidence in function and specificity. | NAD-dependent deacetylase; High confidence in function and specificity. | 0.667 |
ldh | HELO_4099 | HELO_2552 | HELO_4099 | Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Leucine dehydrogenase - Bacillus stearothermophilus (Geobacillus stearothermophilus),InterPro: Glu/Leu/Phe/Val dehydrogenase C terminal, Specificity unclear; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Cytochrome P450; Fatty acid synthase - Bos taurus (Bovine),InterPro: Cytochrome P450, High confidence in function and specificity. | 0.403 |
ldh | nadE | HELO_2552 | HELO_1328 | Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Leucine dehydrogenase - Bacillus stearothermophilus (Geobacillus stearothermophilus),InterPro: Glu/Leu/Phe/Val dehydrogenase C terminal, Specificity unclear; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.511 |
ldh | sIR2 | HELO_2552 | HELO_1142 | Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Leucine dehydrogenase - Bacillus stearothermophilus (Geobacillus stearothermophilus),InterPro: Glu/Leu/Phe/Val dehydrogenase C terminal, Specificity unclear; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | NAD-dependent deacetylase; High confidence in function and specificity. | 0.649 |
nadE | HELO_4099 | HELO_1328 | HELO_4099 | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Cytochrome P450; Fatty acid synthase - Bos taurus (Bovine),InterPro: Cytochrome P450, High confidence in function and specificity. | 0.518 |
nadE | ldh | HELO_1328 | HELO_2552 | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Leucine dehydrogenase - Bacillus stearothermophilus (Geobacillus stearothermophilus),InterPro: Glu/Leu/Phe/Val dehydrogenase C terminal, Specificity unclear; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.511 |
nadE | nadR | HELO_1328 | HELO_2550 | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | Bifunctional NMN adenylyltransferase/Nudix hydrolase [Includes: Nicotinamide-nucleotide adenylyltransferase -Synechocystis sp. (strain PCC 6803),InterPro: Cytidylyltransferase, High confidence in function and specificity. | 0.975 |
nadE | sIR2 | HELO_1328 | HELO_1142 | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | NAD-dependent deacetylase; High confidence in function and specificity. | 0.476 |
nadR | HELO_1141 | HELO_2550 | HELO_1141 | Bifunctional NMN adenylyltransferase/Nudix hydrolase [Includes: Nicotinamide-nucleotide adenylyltransferase -Synechocystis sp. (strain PCC 6803),InterPro: Cytidylyltransferase, High confidence in function and specificity. | Hypothetical protein; tRNA pseudouridine synthase D - Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039),InterPro: Protein of unknown function YGGT, Hypothetical protein. | 0.426 |
nadR | nadE | HELO_2550 | HELO_1328 | Bifunctional NMN adenylyltransferase/Nudix hydrolase [Includes: Nicotinamide-nucleotide adenylyltransferase -Synechocystis sp. (strain PCC 6803),InterPro: Cytidylyltransferase, High confidence in function and specificity. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.975 |
nadR | sIR2 | HELO_2550 | HELO_1142 | Bifunctional NMN adenylyltransferase/Nudix hydrolase [Includes: Nicotinamide-nucleotide adenylyltransferase -Synechocystis sp. (strain PCC 6803),InterPro: Cytidylyltransferase, High confidence in function and specificity. | NAD-dependent deacetylase; High confidence in function and specificity. | 0.507 |
sIR2 | HELO_1141 | HELO_1142 | HELO_1141 | NAD-dependent deacetylase; High confidence in function and specificity. | Hypothetical protein; tRNA pseudouridine synthase D - Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039),InterPro: Protein of unknown function YGGT, Hypothetical protein. | 0.777 |
sIR2 | HELO_4099 | HELO_1142 | HELO_4099 | NAD-dependent deacetylase; High confidence in function and specificity. | Cytochrome P450; Fatty acid synthase - Bos taurus (Bovine),InterPro: Cytochrome P450, High confidence in function and specificity. | 0.667 |
sIR2 | ldh | HELO_1142 | HELO_2552 | NAD-dependent deacetylase; High confidence in function and specificity. | Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Leucine dehydrogenase - Bacillus stearothermophilus (Geobacillus stearothermophilus),InterPro: Glu/Leu/Phe/Val dehydrogenase C terminal, Specificity unclear; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.649 |
sIR2 | nadE | HELO_1142 | HELO_1328 | NAD-dependent deacetylase; High confidence in function and specificity. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.476 |
sIR2 | nadR | HELO_1142 | HELO_2550 | NAD-dependent deacetylase; High confidence in function and specificity. | Bifunctional NMN adenylyltransferase/Nudix hydrolase [Includes: Nicotinamide-nucleotide adenylyltransferase -Synechocystis sp. (strain PCC 6803),InterPro: Cytidylyltransferase, High confidence in function and specificity. | 0.507 |