STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysEProbable serine acetyltransferase - Azotobacter chroococcum mcd 1,InterPro: Serine O-acetyltransferase,High confidence in function and specificity. (295 aa)    
Predicted Functional Partners:
cysM
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.992
cysS
Cysteinyl-tRNA synthetase - Methylococcus capsulatus,InterPro: Cysteinyl-tRNA synthetase class Ia,High confidence in function and specificity; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.967
sdaB
L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.916
iscR
Transcriptional regulator, BadM/Rrf2 family; HTH-type transcriptional regulator iscR - Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum),InterPro: Protein of unknown function UPF0074, High confidence in function and specificity.
 
   
 0.884
serB
Phosphoserine phosphatase - Escherichia coli O157:H7,InterPro: Phosphoserine phosphatase SerB, High confidence in function and specificity.
    
 0.873
hom
Homoserine dehydrogenase.
  
  
 0.846
glyA2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.832
glyA1
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.832
iscS
Cysteine desulfurase - Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578),InterPro: Aminotransferase class V, High confidence in function and specificity.
     
 0.808
trpB
Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.807
Your Current Organism:
Halomonas elongata
NCBI taxonomy Id: 768066
Other names: H. elongata DSM 2581, Halomonas elongata ATCC 33173, Halomonas elongata DSM 2581, Halomonas elongata str. DSM 2581, Halomonas elongata strain DSM 2581
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